Ozempic and Rybelsus have risen in popularity as weight loss medications, yet many remain unaware of their specific benefits, usage guidelines, and potential side effects. This article will cover their uses, potential up- and downsides, purchasing avenues, and suitability for individuals, offering essential information for those looking to such medication on their weight management journey.
Ozempic is a prescription drug known for its efficacy in managing diabetes and aiding weight loss. It is one of the popular brand names for semaglutide, which belongs to a class of medications called glucagon-like peptide-1 receptor agonists (GLP-1 RAs). This drug, administered via injection, regulates blood sugar and appetite, making it a potentially useful tool for individuals striving for better metabolic health. Ozempic is similar to another drug, Wegovy; however, the latter is mainly prescribed for weight loss and long-term weight management.
This medication falls in the same medical category as Ozempic, but with a key difference: it’s the first of its kind that can be taken orally. Targeting similar health outcomes, this medication offers an alternative for those seeking the benefits of GLP-1 RAs without injections, broadening the options for diabetes and weight management.
Semaglutides work by mimicking the action of the GLP-1 hormone, which helps lower blood sugar levels after eating. This then slows down stomach emptying to make you feel fuller for longer and reduces your appetite.
To better understand how this drug works, you can imagine your body as a car and food as its fuel. Semaglutides work like a smart fuel gauge that tells your car it’s fuller than it actually is, leading you to “refuel” less often. Additionally, they act as an efficient fuel manager, making sure the car uses its fuel more effectively, burning it at a slower, more consistent rate to keep it running smoothly for longer. This way, you end up using some of the stored fuel (fat) without needing to top up as frequently, leading to weight loss.
While primarily approved for managing type 2 diabetes, these medications have been established as both safe and effective for weight loss in various clinical trials.
In one clinical trial published by the College of Family Physicians Canada, when 2.4 mg of semaglutide was subcutaneously administered weekly (together with positive lifestyle changes), an average 10% to 15% weight loss (10 to 15 kg) over 68 weeks was observed. Similarly, a separate clinical trial published in The Lancet found that individuals treated with a daily 50 mg dose of oral semaglutide attained an average weight loss of approximately 15.1% over a 68-week period.
However, their safe use comes with an understanding of potential side effects, which can be different for every individual. Hence, it is important for individuals considering these medications for weight loss to consult with healthcare professionals. This ensures a tailored approach, considering personal health profiles and safe pursuit of weight management goals.
Aside from weight loss and managing diabetes, semaglutides offer additional health benefits, including:
According to data from Novo Nordisk’s SELECT Trial, semaglutides could lower the risk of major adverse cardiovascular events such as heart attack, stroke, and cardiovascular death for overweight or obese individuals with established cardiovascular disease (CVD) and no prior history of diabetes.
By mimicking the GLP-1 hormone, which signals fullness to the brain, semaglutides can lead to reduced appetite and help individuals adopt healthier eating habits.
Some patients may experience improvements in their blood lipid profiles, including reductions in LDL (bad) cholesterol levels, which further contribute to cardiovascular health.
A study published in the journal “Kidney International” suggests that semaglutides may have anti-inflammatory properties, which could benefit a range of health conditions, though more studies are needed to fully understand this aspect.
Make sure that the medication in the pen is clear and colourless. Then, attach a new needle by pushing down on the needle cap and turning it until it is tight. Then, pull off both needle caps.
Turn the dose selector until the dose counter shows the flow check symbol, then press and hold the dose button until the counter shows 0. There should be a drop of medication at the tip of the needle.
Turn the dose selector until the dose counter shows the correct dose you need depending on your prescription.
Insert the needle into your stomach (abdomen), thigh, or upper arm. Press and hold the dose button with your thumb until the dose counter reaches 0, then slowly count to 6 before carefully removing the needle.
Carefully remove the needle and place it in a sharps container. Then put the pen cap back on the pen.
Do note to never inject your pen into a muscle or vein and to change your injection site with each injection.
When considering these semaglutides, it’s essential to be aware of their side effects. Some of the more common issues reported by users include:
While these are generally manageable and may decrease over time, there are also less common but more serious side effects to be vigilant about. These include pancreatitis, vision changes, hypoglycemia (low blood sugar), kidney issues, severe allergic reactions, and gallbladder problems. If you encounter any of these side effects, stop the treatment and contact your healthcare provider immediately. They can offer guidance on how to manage these reactions effectively and adjust your treatment plan if necessary, ensuring your safety and well-being while on these medications.
Semaglutides are particularly suited for adults with type 2 diabetes who need to improve their blood sugar levels and also for those who are looking to manage their weight. These medications can be especially beneficial for individuals who are experiencing weight-related issues such as hypertension, high cholesterol, or sleep apnea, and have struggled with weight loss through diet and exercise alone. Semaglutides are an additional tool for these individuals to reduce their appetite and have greater control over their caloric intake.
It is important to know that these medications are not available over the counter and require a doctor’s prescription. However, not all clinics in Singapore stock these drugs, and the prices for semaglutides like Ozempic may vary depending on the clinic. It is advisable to contact the clinic in advance to confirm their availability and prices if you are interested in this treatment option.
For those exploring semaglutide for weight management, there are licensed medical service providers, like Elevate, that offer weight loss programs designed to support your weight loss journey.
Firstly, these medications are not intended for patients with type 1 diabetes or for use as a primary treatment for weight loss without diabetes. This is because they work by affecting insulin and blood sugar levels, which are managed differently in type 1 diabetes and in individuals without diabetes.
Secondly, for those with a history of pancreatitis, diabetic retinopathy, or thyroid cancer, semaglutides may pose additional risks. Such conditions can be exacerbated by the medication’s effects on the body. Additionally, it is advised for pregnant or breastfeeding individuals or those planning to get pregnant to consult with their doctor to adjust their treatment plan accordingly.
Discussing your complete medical history with your healthcare provider is crucial before starting semaglutides as it helps assess the medication’s safety and efficacy for your specific health needs.
If you discontinue semaglutide treatment, there is a possibility that your weight may rebound. This is primarily because the medication’s effects on appetite suppression and blood sugar regulation will cease. Since semaglutides facilitate weight management by helping control cravings and reducing calorie intake; without the medication, old eating habits may resurface, leading to weight gain.
It is therefore important to maintain a healthy lifestyle, including a balanced diet and regular physical activity, even after stopping the medication, to sustain weight loss achievements and prevent rebound weight gain.
Embarking on your weight loss journey is a powerful step towards embracing a healthier, more vibrant version of yourself. It is not just about shedding pounds; it is about gaining energy, improving your well-being, and unlocking the joy of living life to its fullest.
Your weight loss journey is a testament to your strength and commitment to well-being. Let today be the day you take that first step towards a brighter, healthier future where every moment is lived to its absolute best.
Weight loss can significantly alleviate common conditions such as type 2 diabetes, high blood pressure, heart disease, joint pain, and sleep apnea. Shedding excess pounds reduces the strain on your body, improving overall health and enhancing quality of life.
While taking semaglutides, focus on a diet rich in whole foods, lean proteins, vegetables, fruits, and whole grains. These foods support blood sugar control and promote satiety, aligning with the medication’s effects on appetite reduction and weight management efforts.
If you’ve missed your dose, you should take the missed dose as soon as possible. It is not advisable to take an extra dose or an increased dose to make up for the missed dose. If you’ve missed taking your medication for 3 days or more, you should contact your doctor for assistance, as you may have to restart your treatment.
You can store your new, used Saxenda pen in the fridge at 2°C-8°C (36°F-46°F). After the first use, you can continue storing it in the fridge or at a room temperature of 15°C-36°C (59°F-86°F) for up to 30 days.
